Congenital Toxoplasmosis
Treatment
MIND: There exist many different treatment-schemes.
No warranty
Check indications, contraindications and side effects
Any maternal infection should be treated with antibiotic
drugs until delivery, a fetal infection too.
The newborn baby (after diagnosis of a fetal infection
or diagnosed at/after birth) should be treated, too!
Treatment of pregnant women
Before 16th weeks' gestation
4 weeks Spiramycine [Rovamycine©]
After 16th weeks' gestation
- until You get the result of fetal diagnostics, or if
- fetus is infected, or if
- no fetal diagnostic available and a high risk for fetal infection
[= Seroconversion, or persistend IgM in the 2nd or 3rd Trimenon]:
alternating to birth 4 weeks combination
of:Pyrimethamin [Daraprim©], Sulfadiazin, Folinic Acid
4 weeks Spiramycine [Rovamycine©]
After 16th weeks' gestation, if fetus is not infected:
Spiramycine [Rovamycine©] to birth
The combination of:Pyrimethamin [Daraprim©], Sulfadiazin,
can pass through placenta and treat the fetus. But it is not allowed
to give before about 16th weeks' gestation.
Treatment of prenataly infected children
Treatment of prenataly infected children with overt (symptomatic)
disease
6 months: Combination of: Pyrimethamin
[Daraprim©) Sulfadiazin Folinic Acid
6 months: alternating to the first birthday 4
weeks Spiramycine [Rovamycine©] 4 weeks Pyrimethamin
[Daraprim©], Sulfadiazin, Folinic Acid In case of
signs of acute inflammation: Corticosteroids (Prednisolon)
Treatment of prenataly infected children with subclinical
infection (no symptoms)
- 6 weeks: A Combination of:
- Pyrimethamin [Daraprim©]
- Sulfadiazin
- Folinic Acid
- 6 weeks: B
- Spiramycine [Rovamycine©]
- alternating A and B to the first birthday
- 4 weeks Pyrimethamin [Daraprim©], Sulfadiazin, Folinic
Acid
- 6 weeks Spiramycine [Rovamycine©]
Congenital Toxoplasmosis
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last changed: August 20th, 2000.